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2022
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Cerutti G, Rapp M, Guo Y, Bahna F, Bimela J, Reddem ER, Yu J, Wang P, Liu L, Huang Y, Ho DD, Kwong PD, Sheng Z, Shapiro L. Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies. Structure 2021; 29(7):655-663.
Resnick S, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Lin FY, Nair M, Huang Y, Lee S, Tay NES, Rovis T, Yang HW, Xing L, Stockwell B, Ho DD, Chavez, A. Inhibitors of coronavirus 3CL proteases protect cells from protease-mediated cytotoxicity. J. Virol. 2021; 95(14):e0237420.
Xu J, Xu K, Jung S, Conte A, Lieberman J, Muecksch F, Lorenzi JCC, Park S, Schmidt F, Wang Z, Huang Y, Luo Y, Nair M, Wang P, Schulz JE, Tessarollo L, Bylund T, Chuang GY, Olia AS, Stephens T, Teng IT, Tsybovsky Y, Zhou T, Munster V, Ho DD, Hatziioannou T, Bieniasz P, Nussenzweig MC, Kwong PD, Casellas R. Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants. Nature 2021; 595(7866):278-282.
Wang P, Casner RG, Nair MS, Wang M, Yu J, Cerutti G, Liu L, Kwong PD, Huang Y, Shapiro L, Ho DD. Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization. Cell Host & Microbe 2021; 29(5):747-751.
Annavajhala MK, Mohri H, Wang P, Nair M, Zucker JE, Sheng Z, Gomez-Simmonds A, Kelley AL, Tagliavia M, Huang Y, Bedford T, Ho DD, Uhlemann AC. Emergence and expansion of SARS-CoV-2 B.1.526 after indentification in New York. Nature 2021; 597(7878):703-708.
Wang P, Nair MS, Liu L, Iketani S, Luo Y, Guo Y, Wang M, Yu J, Zhang B, Kwong PD, Graham BS, Mascola JR, Chang JY, Yi MT, Sobieszczyk M, Kyratsous CA, Shapiro L, Sheng Z, Huang Y, Ho DD. Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7.. Nature 2021; 593(7837):130-135.
Mack CD, DiFiori J, Tai CG, Shiue KY, Grad YH, Anderson DJ, Ho DD, Sims L, LeMay C, Mancell J, Maragakis LL. SARS-CoV-2 transmission risk among national basketball association players, staff, and vendors exposed to individuals with positive test results after COVID-19 recovery during the 2020 regular and postseason.JAMA 2021; 181(7):960-966.
Cerutti G, Guo Y, Zhou T, Gorman J, Lee M, Rapp M, Reddem E, Yu J, Bahna F, Bimela J, Huang Y, Katsamba PS, Liu L, Nair M, Rawi R, Olia AS, Wang P, Zhang B, Chuang GY, Ho DD, Sheng Z, Kwong PD, Shapiro L. Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host & Microbe 2021; S1931-3128(21)00133-5.
Rapp M, Guo Y, Reddem ER, Yu J, Liu L, Wang P, Cerutti G, Katsamba P, Bimela JS, Bahna FA, Mannepalli SM, Zhang B, Kwong PD, Huang Y, Ho DD, Shapiro L, Sheng Z. Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-Derived Antibody Class. Cell Rep. 2021; 35(1):108950.
Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair M, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature Comm. 2021; 12(1):2708.
Kissler SM, Fauver JR, Mack C, Olesen SW, Tai C, Shiue KY, Kalinich CC, Jednak S, Ott IM, Vogels CBF, Wohlgemuth J, Weisberger J, DiFioris J, Anderson DJ, Mancell J, Ho DD, Grubaugh ND, Grad YH. Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies. Plos Biology 2021; 19(7):e3001333.
Banach BB, Cerutti G, Fahad AS, Shen CH, Oliveira de Souza M, Katsamba PS, Tsybovsky Y, Wang P, Nair MS, Huang Y, Francino-Urdániz IM, Steiner PJ, Gutiérrez-González M, Liu L, Lopez Acevedo SN, Nazzari AF, Wolfe JR, Luo Y, Olia AS, Teng IT, Yu J, Zhou T, Reddem ER, Bimela J, Pan X, Madan B, Laflin AD, Nimrania R, Yuen KY, Whitehead TA, Ho DD, Kwong PD, Shapiro L, DeKosky BJ. Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses. Cell Reports 2021; 37(1):109771.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Xuming Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Dong Xu, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S. Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature 2021; 589(7841):270-275.
2020
Jia M, Liberatore R, Guo Y, Chan K-W, Pan R, Lu H, Waltari E, Mittler E, Chandran K, Finzi A, Kaufmann D, Seaman M, Ho D, Shapiro L, Sheng Z, Kong X-P, Bieniasz P and Wu X. VSV-displayed HIV-1 envelope identifies broadly neutralizing antibodies class-switched to IgG and IgA. Cell Host & Microbe 2020, 27: 963-975.e5.
Lu M, Uchil PD, Li W, Zheng D, Terry DS, Gorman J, Shi W, Zhang B, Zhou T, Ding S, Gasser R, Prevost J, Beaudoin-Bussieres G, Anand SP, Laumaea A, Grover JR, Liu LH, Ho DD, Mascola J, Finzi A, Kwong PD, Blanchard SC, Mothes W. Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles. Cell Host & Microbe 2020; 28(6):880-891.
Meyers K, Price D, & Golub S. Behavioral and social science research to support accelerated and equitable implementation of long-acting pre-exposure prophylaxis. Current Opinions in HIV/AIDS. 2020; 15(1):66-72.
Liu C & Meyers K. Beyond clinical trials: social outcomes of structured stakeholder engagement in biomedical HIV prevention trials in China. Culture, Health, and Sexuality.2020;22(12):1365-1381.
Golub S, Meyers K, & Enemchukwa C. Perspectives and Recommendations from LGBTQ Youth of Color regarding Engagement in Biomedical HIV Prevention. Journal of Adolescent Health. 2020; 66(3):281-287.
Castor D, Meyers K, & Allen, S. The only way is up: priorities for implementing long-acting antiretrovirals for HIV prevention and treatment Current Opinions in HIV/AIDS. Review. 2020; 15(1):73-80.
Rong F, Kutner B, Wu Y, Xie L, Hou J, Meng S, Gu Y, Xu H, Huang Z, He N, Meyers K. Do gay and bisexual men who conceal their same-sex behavior prefer different kinds of health services? Findings across four cities to inform client-centered HIV prevention in China. BMC Public Health. 2020; 6;20(1):4.
Sabo, Y., de Los Santos, K., and Goff, S.P. (2020) IQGAP1 negatively regulates HIV-1 Gag trafficking and virion production. Cell Rep. 30, 4065-4081.e4.
Mogus AT, Liu L, Jia M, Ajayi DT, Xu K, Kong R, Huang J, Yu J, Kwong PD, Mascola JR, Ho DD, Tsuji M, Chackerian B. 2020. Virus-Like Particle Based Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide. Vaccines (Basel). 8: E765.
Huang J, Zhou J, Ghinnagow R, Seki T, Iketani S, Soulard D, Paczkowski P, Tsuji Y, MacKay S, Cruz LJ, Trottein F, Tsuji M. 2020. Targeted Co-delivery of Tumor Antigen and α-Galactosylceramide to CD141+ Dendritic Cells Induces a Potent Tumor Antigen-Specific Human CD8+ T Cell Response in Human Immune System Mice. Front Immunol. 11: 2043.
Coelho-dos-Reis JGA, Funakoshi R, Huang J, Pereira FV, Iketani S, Tsuji M. 2020. Functional Human CD141+ Dendritic Cells in Human Immune System Mice. J. Infect. Dis. 221:201-213.
Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Lopez Acevedo SN, Madan B, deSouza MO, Pan X, Wang P, Wolfe JR, Yin MT, Ho DD, Phung E, DiPiazza A, Chang LA, Abiona OM, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L, Kwong PD. Structure-based design with tag-based purification and in-process biotinylation enable streamlined development of SARS-CoV-2 spike molecular probes. Cell Rep. 2020; 33(4):108322.
Zhou T, Tsybovsky Y, Gorman J, Rapp N, Cerutti G, Chuang GY, Katsamba PS, Sampson JM, Schon A, Bimela J, Boyington JC, Nazzari A, Olia AS, Shi W, Sastry M, Stephens T, Stuckey J, Teng IT, Wang P, Wang S, Zhang B, Friesner RA, Ho DD, Mascola JR, Shapiro L, Kwong PD. Cryo-EM structures of SARS-CoV-2 spike without and with ACE2 reveal a pH-dependent switch to mediate endosomal positioning of receptor-binding domains. Cell Host & Microbe 2020; 9;28(6):867-879.
Liu L, Wang P, Nair MS, Yu J, Rapp MA, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Potent neutralizing antibodies against multiple epitopes on the SARS-CoV-2 spike. Nature 2020; 584(7821):450-456. PMID: 32698192.
Wang P, Liu L, Nair M, Yin MT, Luo Y, Wang Q, Yuan T, Mori K, Solis AG, Yamashita M, Purpura LJ, Laracy JC, Sodroski J, Huang Y, Ho DD. SARS-CoV-2 neutralizing antibody responses are more robust in patients with severe disease. Emerg. Microb. Infect. 2020;9(1):2019-2093. PMID: 32930052.
Andrews CD, Huang Y, Ho DD, Liberatore RA. In vivo expressed biologics for infectious disease prophylaxis: rapid delivery of nucleic acid-based antiviral antibodies. Emerg. Microb. Infect. 2020; 9(1);1523-1533.
Garg A, Liu L, Ho DD, Joshua-Tor L. Heterologous expression and purification of SARS-CoV-2 nubleocapsid protein. BioProtocals, 2020; Bio-101:e5005.
Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F, Zhang T, Kim TW, Harschnitz O, Redmond D, Liu C, Naji A, Ciceri G, Guttikonda S, Bram Y, Nguyen D, Cioffi M, Chandar V, Hoagland D, Huang Y, Xiang J, Wang H, Chen HJ, Studer L, Pan FC, Ho DD, tenOever BR, Evans T, Schwartz RE, Chen S. A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids. Cell Stem Cell 2020; 27(1):125-136.
Duan F, Guo L, Yang L, Han Y, Thakur A, Nilsson-Payant BE, Wang P, Zhang Z, Ma CY, Han T, Zhang T, Wang X, Xu D, Duan X, Xiang J, Tse HF, Liao C, Luo W, Evans T, Schwartz RE, tenOever B, Ho DD, Chen S, Lian Q, Chen HJ. Modeling COVID-19 with human pluripotent stem cell-derived cells reveals synergistic effects of anti-inflammatory macrophages with ACE2 Inhibition against SARS-CoV-2. Research Square, 2020; rs.3.rs-62758.
Wang P, Gajjar MR, Yu J, Padte NN, Gettie A, Blanchard JL, Russell-Rodrique K, Liao LE, Perelson AS, Huang Y, Ho DD. Quantifying the contribution of Fc-mediated effector functions to the antiviral activity of of anti-HIV-1 antibodies in vivo. Proc. Natl. Acad. Sci. USA 2020; 117(30):18002-18009.
Jia X, Liberatore RA, Guo Y, Chan KW, Pan R, Lu H, Waltari E, Mittler E, Chandran K, Finzi A, Kaufmann DE, Seaman MS, Ho DD, Shapiro L, Sheng Z, Kong XP, Bieniasz PD, Wu X. VSV-displayed HIV-1 envelope identifies broadly neutralizing antibodies class-switched to both IgG and IgA. Cell Host & Microbe 2020; 27:1-13.
Guttman M, Padte NN, Yu J, Huang Y, Rocklin G, Scian M, Ho DD, Lee KK. The influence of proline isomerization on potency and stability of anti-HIV antibody 10E8. Sci. Rep. 2020; 10(1):14313.
Rathore A, Iketani S, Wang P, Jia M, Sahi V, Ho DD. CRISPR-based gene knockout screens reveal deubititinases involved in HIV-1 latency in two Jurkat cell models. Sci. Rep. 2020; 10:5350-5363.
Mukhopadyay M, Galperin M, Patgaonkar, Vasan S, Ho, DD, Nouel A, Claireaux M, Benati D, Lambotte O, Huang Y, Chakrabarti LA. DNA vaccination by electroporation amplifies broadly cross-restricted public TCR clonotypes shared with HIV controllers. J. Immunol. 2020; 199(10):3427-3452.
